Formula 82S

A Proprietary Formulation of Natural and Eco-Certified Ingredients for Better Hair Health

Formula 82S is a 3-in-1 (shampoo + conditioner + anti-hair loss) product that strengthens hair fibers, restores soft, natural texture to damaged hair, and helps prevent hair loss. It’s a great choice for people who are undergoing hair restoration, as it contains an industry-leading level (2%) of Saw Palmetto, a botanically derived 5-alpha reductase inhibitor shown in studies to reduce DHT, a leading cause of hair loss. Unlike lower-quality shampoos that contain sulfates, parabens, and silicone, which can damage new hair growth, Formula 82S uses gentle, natural cleansers and conditioning agents.

In addition to Saw Palmetto, Formula 82S contains a blend of natural extracts, amino acids, and vitamins that help new hair grow stronger, and existing hair recover its vitality. The formula was recently updated to include even more Saw Palmetto, and improved surfactants and conditioning agents, resulting in better sudsing and conditioning. With Formula 82S, most users report that they do not need a separate conditioner for their hair to be left feeling soft, healthy, and easy to comb.

It is an excellent choice for people who want to support healthy hair growth, and an excellent complement to a daily regrowth regimen, such as one involving Formula 82M (for men and women), or Formulas 82F82D (for men only).

If you are an individual and would like to purchase Formula 82S, click here.
If you are in Canada, contact our partners Pure Integrative Pharmacy for more information.
If you are interested in carrying 82S in your clinic, spa, salon, or practice, fill out the form below.
US patients can purchase Formula 82S directly, here.
Canadian patients can purchase 82S directly, here.
If you would like to carry 82S in your clinic, click here.
Excellent Complement to Patients’ Regrowth Regimen

“Our office has had great success with 82S. We have combined 82S with 82M and PRP hair restoration. We have multiple patients that have the shampoo shipped to them from our office about every three months, so the shampoo seems to last.”

Helps Reduce DHT to Fight Hair Loss

A major contributing factor in Androgenetic Alopecia (AGA) is the conversion of Testosterone to Dihydrotestosterone (DHT) via the enzyme 5-α Reductase (5AR).

Dihydrotestosterone (DHT) and Hair Loss

For many years, scientists thought that androgenetic alopecia was caused by the predominance of the male sex hormone, testosterone, which women also have in trace amounts under normal conditions. While testosterone is at the core of the balding process, DHT is thought to be the main culprit. Testosterone converts to DHT with the aid of the enzyme Type II 5-alpha reductase, which is held in a hair follicle's oil glands. Scientists now believe that it's not the amount of circulating testosterone that's the problem, but the level of DHT binding to receptors in scalp follicles. DHT shrinks hair follicles, making it impossible for healthy hair to survive.

McAndrews PJ. "Women's Hair Loss / Causes of Hair Loss". American Hair Loss Association

Formula 82S hair loss shampoo contains the active ingredient Serenoa Repens (Saw Palmetto), a natural, botanically-derived 5-alpha reductase inhibitor that has been shown in studies to help reduce DHT production and prevent hair loss.

Made From Natural and Eco-Certified Ingredients

We understand, it is hard when shopping to tell the difference in the source and quality of components in shampoos. It doesn’t help that many compounds found in nature have names that are not easily pronounced (and have several names in some cases). We try to make it easier on our users by using only high quality, naturally-sourced components in our shampoos. And have worked hard to avoid adding any manufactured or synthetic ingredients to them. The difference is that 82S’ natural ingredients and eco-certified cleansers are better for the Earth (and your hair too). The surfactants and conditioning agents used in 82S Hair Loss Shampoo are 100% eco-certified and biodegradable. Not many shampoos can say that. We have the lab certification to prove it.


SAW PALMETTO (SERENOA REPENS): A contributing factor in Androgenetic Alopecia (AGA) is the conversion of Testosterone to Dihydrotestosterone (DHT) via the enzyme 5-α Reductase (5AR). Serenoa Repens is a botanically-derived 5AR inhibitor that has been shown in studies to have a positive effect in reducing hair loss.

L-GLUTAMIC AMINO ACID & COCONUT FATTY ACIDS: Eco-certified surfactants that are plant-derived and biodegradable. In addition to providing gentle cleansing, this combination exhibits excellent conditioning properties that leaves hair feeling silky.


AMINO ACIDS (PROPRIETARY AMINO ACID COMPLEX): Strengthen the structure of hair and serve as a precursor to hair growth functions such as cellular metabolism and the synthesis of hair proteins. Our specially formulated Amino Acid compound has been shown in studies to lead to increased tensile strength in hair.

BIOTIN (WATER SOLUBLE B-VITAMIN): A vital substance for hair health. Stimulates the proliferation and differentiation of Keratinocytes, and improves hair's natural barrier function by promoting the formation of intercellular lipids and reducing transepidermal water loss.

PHYTOKERATINE (THERMAL PROTECTANT): Prevents damage from daily sources of heat and UV, and reduces the prevalence of Trichoptilosis (split ends) in hair. Returns strength and vitality to damaged hair.

VITAMIN A (FAT SOLUBLE ANTIOXIDANT): A powerful anti-oxidant that prevents and repairs cell and tissue damage. Vitamin A's effectiveness as a hair loss prevention component is well documented—it is commonly advised by physicians to reduce hair loss for people taking chemotherapy drugs such as Doxorubicin.

BABASSU OIL (NATURALLY OCCURRING FATTY ACID): Eco-certified, plant-derived oil with cleansing and foaming properties. Conditions and repairs.

PANTHENOL (PROVITAMIN 5): Readily binds to the hair shaft, assisting hair in increasing and retaining its natural moisture. Helps fortify collagen in hair, promoting elasticity and hair strength.

SEAWEED EXTRACT (A NATURAL SOURCE OF VITAMINS & ANTIOXIDANTS): A natural source of essential vitamins and minerals as well as antioxidants that aid in skin cell and hair elasticity, and help keep hair and skin revitalized, moisturized and protected (from environmental pollutants and damaging free radicals). Has natural cleansing and balancing properties linked to the reduction of skin oiliness and sebum production.

Balanced Cleansing without Causing Hair Damage

Overview of Terms Used in Hair Products

Surfactants (cleansing agents). Compounds that lower the surface tension between two liquids, or between a liquid and a solid (typically through sudsing). Surfactants can act as detergents, wetting agents, foaming agents and dispersants. Surfactants perform the cleaning function at the heart of most shampoos.

Absorption (combining, sometimes referred to as penetration). Process in which one molecule dissolves into another uniformly. Once absorption takes place, it cannot easily be undone; in other words, the two molecules (or groups of molecules) cannot be easily separated.

Adsorption (adhering to). The process in which a molecule adheres to the surface of another, through weak (typically electromagnetic) forces. For example, Humectant molecules attract negatively-charged Oxygen atoms in water. This (-OH) hydrogen bonding promotes the migration and retention of water around the shaft of the hair.

Humectants (also referred to as moisturizers). Prevent loss of moisture, and in some cases, have the ability to actively attract moisture. Highly effective humectants can adsorp (or attract and hold) up to three times their weight in water.

pH (The measure of acidity of a substance). Most modern shampoos and conditioners are formulated to be slightly acidic, having a pH around that of the hair’s acid mantle (4.0-5.0). Hair that is close to its ideal pH of 4.5–5.0 is generally considered to be at its peak strength.

Alkaline products typically cause hair to swell, causing the cuticle to lift and remove oils from the air. This results in frizzy, dull, brittle hair that is prone to breakage and tangling. Extremely alkaline solutions cause the disulfide bonds between Keratin protein molecules to break down, and can eventually dissolve the protein completely. These types of solutions are used to perm or relax the hair, and can be extremely damaging, especially to hair that is already fragile.

Sebum (an oily secretion of the sebaceous glands). Some level of sebum production is healthy and protects skin and hair from environmental damage and prevents dry and cracked skin (including the scalp). However the overproduction and accumulation of sebum can lead to bacteria growth and clogged pores, commonly causing dermatitis, and can negatively affect hair follicles and hair health.

82S contains specially formulated cleansers and conditioners that remove dead skin and build-up and replace vital moisture and oils—in a way that mimics skin and hair’s naturally healthiest state. First, 82S’s pH (~5.2) is very close to that of healthy hair’s mantle. Second, the surfactants in 82S are much gentler than the sulfate-based wetting agents found in the majority of shampoos worldwide. The Glutamic Amino Acid-derived & Coconut Fatty Acid-based cleansers found in 82S offer far more balanced cleansing—and remove surface sebum without affecting hair’s intercellular lipids—compared to Sodium Lauryl Sulfate (SLS), Sodium Laureth Sulfate (SLES), and other sulfate-based cleansers prevalently used in shampoos (due to their high availability and low costs).

Natural Conditioners Leave Hair Soft, Shiny and Easy-to-Comb

A lot of thought and specialized ingredients go into making a quality shampoo (let alone an all natural, hair loss shampoo). On one hand, you have little choice but to remove naturally occurring surface lipids that protect the skin and hair if you want to wash your hair. And for the most part it is much better to remove dead skin and built-up oils from hair so that it doesn’t result in clogged pores and greasy, tangled, limp hair. But the simple truth is shampoos (through the surfactants they contain that cleans the hair) all strip components that the hair and scalp produce on their own, and need to a large extent, in order to remain healthy. Namely, naturally produced oils and moisture. Unless you condition at the same time or immediately after cleaning your hair, you will end up with dry, damaged hair. It’s a fact that most shampoos don’t mention on their labels.

The key aspects of hair health, related to hair loss and hair condition, involve the strength and health of the hair’s roots and the promotion of smooth texture of the hair’s shaft. Aside from Androgenic Alopecia (or genetically-predisposed male and female pattern balding), the single greatest cause of hair loss is physical/mechanical damage—specifically, subjecting hair to forces that exceed its natural tensile strength, causing it to break, or exerting forces on hair follicles that over time lead to damage to the roots of hair.

Let’s examine two common issues:

1) You know that flat irons, bleaching, and blow dryers cause physical damage to hair, but did you know that aside from those things, the force on hair’s roots from styling hair in buns, braids and ponytails over time can cause damage to hair—resulting in hair loss? Women who consistently part their hair or wear their hair in ponytails are among the most treated patients at hair loss clinics. You may not think about it, but by putting force on the roots of your hair, you are actively damaging your hair’s follicles (your hair’s life source and anchor).

2) The simple act of combing your hair in the morning is one of the potentially most damaging things you do to your hair all day. The reason to emphasize ‘potentially’ is because if your hair is properly conditioned—so that it adsorbs sufficient moisture and fatty-acids shortly following cleansing—it becomes more combable. And combability (or the ease with which hair can be detangled and styled) is at the heart of what you want in a hair care product. A high-quality shampoo with conditioning agents (or a separate conditioner) should do one thing well: leave your hair untangled, moist and smooth enough that you can style it without causing damage to your hair’s shaft and roots.

Given that most shampoos and conditioners you find on the shelf at stores will leave your hair feeling somewhat smooth, that bar may seem to be a low one, but patients who have already experienced an appreciable degree of hair loss stand to benefit tremendously from the scientifically-proven increased combability and tensile strength from the use of 82S. In laboratory studies involving both colored (treated) and uncolored (untreated) hair, key components of 82S were shown to increase both the tensile strength and wet combability of hair. To fully appreciate what that means to hair’s health, see what the benefit of these ingredients looks like in terms of smoothness and strength of a single shaft of hair at a molecular level, after extensive simulated styling below:
82S Chart (Amino Acids)

Contains Amino Acids to Strengthen Hair Fibers

Amino Acids, when interactive and bioavailable can strengthen the structure of hair.

Amino Acids in Shampoos and Conditioners

When amino acids are applied to hair in the form of simple aqueous solution, uptake of the amino acids is mainly controlled by ionic equilibrium. When amino acids were incorporated in a hair conditioner, the result was quite different, suggesting the importance of interaction between the amino acids and the cationic surfactants. Uptake of Pyrrolidone Carboxylic Acid (PCA), a derivative of Glutamic Acid, is enhanced by combining with Arginine, an amino with strong affinity towards hair. […] Alanine in a hair conditioner increases hair surface hydrophobicity. Histidine and Phenylalanine improve tensile strength. PCA was proved to be effective to improve color-retention of dyed hair.

Oshimura E (1), Abe H, Oota R. "Hair and amino acids: the interactions and the effects". Journal of Cosmetic Science

Our specially formulated amino acid complex specifically targets mechanisms shown in studies to lead to increased tensile strength in hair, elasticity, moisture affinity, color retention, and damage prevention. The composition of our Amino Acids complex is modeled after the constituent amino acids of protein in the Cell Membrane Complex (CMC), and is known to provide beneficial protection and improve the health of hair. Formula 82S contains a specially formulated complex of amino acids (including Histidine, Phenylalanine, Arginine, Alanine, Serine, Glycine, Valine, Proline, Threonine, Isoleucine, and Phytokeratine).

Nourishes Hair From Root to Tip

At Hair Science, we understand that the average person undertakes some form of normal daily hair management. We specifically formulated 82S to address the realities of typical-use routines—including combing, styling, and drying your hair. We began the formulation of 82S with the inclusion of Saw Palmetto to reduce DHT, to prevent follicle shrinkage and promote healthy development of hair’s roots. We then added natural conditioning agents to restore moisture and oils to hair’s shaft. And finally, we added a series of Amino Acids to strengthen and improve the combability of hair and protect it from environmental damage.

Characteristics of Amino Acids in Hair Health Promotion (pH)

Basic amino acids improve hair strength and shine
Neutral amino acids improve the dry feel of hair (combability, smoothness and silky feel)
Acidic amino acids improve the wet feel of hair (combability and smoothness)

Amino acids applied externally are known to interact with the hair to produce various cosmetic effects, such as moisturizing, strengthening, color-protection and repair of surface damage (Oshimura).

82S Chart (Alanine)

Alanine is a hydrophobic molecule. It is ambivalent, meaning that it can exist inside or outside of the protein molecule. Hair surface hydrophobicity prevents “frizzy” hair. And restoring this natural characteristic of hair indicates the effectiveness of Alanine in promoting the absorption of nourishing oils to the hair shaft—sealing and protecting them.

Use of 82S would significantly reduce the effects of physical damage of combing hair in just a few months if it contained only the amino acids: Histidine, Phenylalanine, and Arginine. But we also added a number of other nourishing conditioners, amino acids, including the thermal protectant, Phytokeratine, to protect hair from thermal damage encountered from drying as well as from daily environmental exposure to UV.

The use of curling irons and other heat sources, as well as excessive application of hair products such as perms and hair coloring strip the protective layering off the outside of the hair's shaft and weaken the hair, making it prone to split ends. Imbalances in the pH of hair and mechanical stresses—including pulling a comb forcefully through tangled hair, repeated combing, and the use of elastics and other hair retention methods cause damage to hair’s shaft and ends.

In addition to the primary focus of the ingredients found in 82S on hair’s roots and shaft, the inclusion of Phytokeratine and other conditioning agents was made to address Trichoptilosis, or split ends, which result from thermal, chemical and mechanical stresses to hair.

Sulfate, Paraben and Silcone Free

Many commonly used hair products contain inexpensive surfactants, known as Sodium Lauryl Sulfate and Sodium Laureth Sulfate (also known as sulfates). Sulfates are effective surfactants, but they are not generally considered to be particularly well-balanced and they cause irritation of the skin and scalp in many people. Sulfate-based products rely on the near complete removal of build-up of your skin’s naturally occurring lipids, which leads to dryness, and creates a cycle in which your skin begins to overproduce sebum as a result.

82S starts out by using surfactants that are as balanced and gentle as possible (more so than essentially every commercially-available shampoo on the market). To counteract the depletion of healthy oils in hair, we include ingredients that help restore the hair’s ability to attract and retain moisture, and condition and coat hair in order to replace natural fatty acids. 82S’s natural conditioners and nourishing agents closely mimic the naturally-occurring oils found in healthy hair and leave hair feeling soft and manageable.

Safe for Color Treated Hair / Promotes Color Retention

Surfactants and conditioners that are mildly acidic have been found to provide longer life to the color of hair that has been dyed. Specifically, the addition of Sodium PCA / Pyrrolidone Carboxylic Acid (which is found in many shampoos that state “For Colored or Treated Hair”) has been shown to improve color retention of dyed hair.

82S Chart (Sodium PCA)

In the above study, color development of red semi-permanent hair dye was shown to be improved by over 80% through the use of post-dye treatment with hair conditioner containing Sodium PCA.

Performance Validated Ingredients in Scientific Studies

Hair Science is first and foremost a research and development company. Our formulas combine well-established ingredients—known to benefit hair and scalp health—with novel formulations and methods that increase their efficacy, stability, and usability. We work with some of the world’s top compounding pharmacies, chemists, and hair experts to ensure that our products are among the safest, most balanced, and most effective on the market.

And unlike many other shampoos and products, we have the certifications, lab tests, and science to back our formulas’ effectiveness claims. Be it 82S’ eco-certification, component tensile strength tests, “color-fast” or wet combability studies, we are happy to match up against other shampoos and providers. As we have complete confidence in the fact that we offer some of the best hair care products available in the world today.

Formula 82S

Are you the owner or operator of a medical spa, salon, or hair restoration clinic whose interested in carrying Formula 82S? Fill out this form and we will send you information on how to get started.